Tottenham continued their good form with a comfortable 2-0 win at Russian side Anzhi Makhachkala in the Europa League, while Swansea, Fiorentina, Valencia and Sevilla also picked up wins.
Jermain Defoe just cannot stop scoring whenever given a run-out from the start, and the Spurs frontman made it seven goals in four starts with the first goal on 34 minutes. Nacer Chadli doubled the lead four minutes later, and there were no real worries for Spurs in the second half, despite Anzhi's best efforts as Tottenham remained perfect with six points from two matches.
At the Liberty Stadium, Swansea had Wayne Routledge to thank for all three points, with the winger's goal seven minutes into the second half enough to give Michael Laudrup's men a 1-0 victory over Swiss side St. Gallen.
Valencia bounced back from that heavy 3-0 defeat to Swansea, by registering a 2-0 win over Kuban Krasnodar to get their Europa League campaign back on track.
"It was a very difficult game for us after losing against Swansea, but I think that the team played very well, concentrated for 90 minutes, scored two goals and won the game," Valencia defender Ricardo Costa said.
"I think Valencia had more possession of the ball, we had more chances to score and Krasnodar only threatened from our mistakes. But I think that 2-0 is a great result for us and more importantly it is three points towards qualification.
"They (Kuban) have players who are very fast, and they play on the counter. But I think that today (Thursday) we did everything to contain Krasnodar."
Costa, though, believes it is Swansea who will pose the biggest threat in the group. "It is open," he added. "Valencia have every possibility to pass to the next round. I think it is Swansea (who are our main rivals). Swansea are a great team."
At the DW Stadium, Championship side Wigan pulled off an impressive 3-1 win over Maribor, with a brace from on-loan Manchester United midfielder Nick Powell and one from Ben Watson helping the F.A. Cup champions to all three points.
Elsewhere, Sevilla trumped German side Freiburg 2-0, while Eintracht Frankfurt eased past APOEL 3-0.
Italian side Fiorentina edged Dnipro 2-1, while Lazio could not pick up all three points on Thursday, settling for a 3-3 draw with Turkish side Trabzonspor.
Lyon were held to their second straight draw after just about managing a 1-1 result with Guimaraes, thanks to an equaliser from Maxime Gonalons, while Bordeaux went down 2-1 to Maccabi Tel Aviv.
Results: Shakhter Karagandy 2-2 Maccabi Haifa; Rubin Kazan 4-0 SV Zulte Waregem; Kuban Krasnodar 0-2 Valencia; Anzhi Makhachkala 0-2 Tottenham Hotspur; Slovan Liberec 2-1 Estoril; Lyon 1-1 Vitoria Guimaraes; Rapid Wien 2-2 Dynamo Kyiv; Legia Warszawa 0-1 Apollon Limassol; AZ Alkmaar 1-1 PAOK; Sevilla 2-0 Freiburg; Trabzonspor 3-3 Lazio; Tromso 1-1 FC Sheriff; Rijeka HNK 1-1 Real Betis; Genk 2-1 FC Thun; Esbjerg 1-2 FC Salzburg; Swansea 1-0 FC St. Gallen; Chornomorets 0-2 PSV Eindhoven; Elfsborg 1-1 Standard Liege; Dnipro 1-2 Fiorentina; APOEL 0-3 Eintracht Frankfurt; Eintracht Frankfurt; Bordeaux 1-2 Maccabi Tel-Aviv; FCM. Tel-Aviv; Pacos de Ferreira 1-1 CS Pandurii; Wigan 3-1 NK Maribor; Ludogorets 3-0 Dinamo Zagreb.