Third seed Andy Murray will begin his title defence against Frenchman Paul-Henri Mathieu, while Australian Open champion Stanislas Wawrinka will be up against Marcos Baghdatis of Cyprus in the second round of the Aegon Championships on Wednesday.
The Brit reached the semifinals of the French Open, before being knocked out by eventual winner Rafael Nadal but he is here as the defending champion. Murray got the better of Mathieu in his five previous meetings with him.
Murray faces a tough task in retaining the title at the Queen's Club. After clearing the second round hurdle, the Wimbledon champion could face Australian Bernard Tomic, before meeting fourth seed Grigor Dimitrov and Wawrinka in the later part of the tournament.
All eyes will be on former Wimbledon champion Amelie Mauresmo, who has joined the world number five's camp as his new coach. Murray is looking forward to competing at the Queen's Club as it is a good preparatory tournament ahead of the Wimbledon.
"I always enjoy coming back here," Murray said. "It is great preparation coming up to Wimbledon and they have a fantastic field again this year. I've had some great years here and some years haven't gone so well, but last year everything worked out perfectly. It was the start of the best summer of my tennis career. I'm excited to get going."
After a disappointing end to the clay court season, Switzerland's Wawrinka will be hoping to begin his Wimbledon preparations with a win against Baghdatis in the second round at the Queen's Club.
Wawrinka faced a shock exit at the French Open when he was stunned by Guillermo Garcia-Lopez of Spain in the first round. The Swiss number one will be aiming to improve his record here as he had lost the second round to James Ward in 2011.
The world number three stressed it is a great chance for him to get used to grass courts ahead of the Wimbledon and is looking forward to playing in London.
"I'm really looking forward to playing and very grateful the tournament saved a wildcard for me," Wawrinka said. "I love London, I love the atmosphere. It is an important tournament with a lot of history, and playing at Queen's Club gives me the best possible chance to become comfortable on grass."
Wawrinka enjoys a perfect record against Baghdatis as he has got the better of him in all four previous meetings. However, the Cyprus star is in great form, after winning Nottingham Challenger event and beating Bradley Klahn in the first round.
Schedule of Play
Feliciano Lopez vs Lleyton Hew starts at 5:00 pm IST, 11:30 am GMT
Andy Murray vs Paul-Henri Mathieu starts at 7:30 pm IST, 2:00 pm GMT
Stanislas Wawrinka vs Marcos Baghdatis starts at 10:00 pm IST, 4:30 pm GMT
Where to Watch Live
The live coverage will be on Star Sports 1 and Star Sports HD 1 in India. Global online viewers can live stream the action HERE, HERE or HERE. ESPN will have live coverage for the US and Australia but to watch the action live online, click HERE or HERE. For UK viewers, BBC and BT Sports will cover the tournament live, with an option to watch online HERE or HERE.